Synthesis
SPS: MBRAUN SPS5
A Solvent Purification System (SPS) is a sealed, inert‑gas‑pressurized setup that passes solvents through activated columns to remove water, oxygen, and trace impurities. It delivers dry, oxygen‑free solvents on demand—avoiding hazardous glass‑still distillation—improving safety, speed, and reproducibility. Common uses include air‑/moisture-sensitive chemistry, glovebox refills, and routine solvent preparation in research labs, targeting complex organocatalyst complexes.
Automated flash column chromatography: MD Scientific PuriFlash® PF-XS 520 plus (two machines)
An organic column machine (automated flash chromatography) uses pressure driven flow of organic eluents through commercial packed silica columns; compounds separate by differential adsorption/desorption governed by polarity and solvent strength (isocratic or gradient elution).
Integrated UV/Vis detection tracks elution profiles and triggers fraction collection for reproducible, scalable purification.
Typical uses: purifying reaction mixtures, removing by products/starting materials, and isolating natural products from mg to multi gram scale with eluents like heptane, EtOAc, MeOH etc.
Schlenk lines
A Schlenk line is a dual‑manifold glass apparatus (vacuum and inert gas) with stopcocks and cold traps, enabling air‑/moisture‑sensitive manipulations under argon or nitrogen while safely evacuating to low pressures.
It supports evacuate/backfill cycles, inert transfers, solvent/reagent degassing, and drying/activation under vacuum with overpressure protection via a bubbler.
Uses include organometallic and radical chemistry, preparing Grignard/catalyst solutions, purifying/degassing solvents, handling pyrophoric reagents, and storing samples under inert atmosphere, organo-catalytic synthesis. This is a nice complementary set-up to our gloveboxes. Allowing for more work simultaneously.
Gloveboxes: MBRAUN UNIlab pro glovebox
A glovebox is a sealed, recirculating argon‑gas enclosure with integrated O₂/H₂O scrubbers, pressure control, antechambers, and glove ports, enabling manipulation without atmospheric exposure. It provides safe handling, weighing, formulation, and storage of air‑/moisture‑sensitive or pyrophoric materials; supports device/cell assembly, vial sealing, and drying/packaging under inert conditions. Typical operations include preparing catalyst/organometallic solutions, solvent transfer, Schlenk‑to‑glovebox transfers via the antechamber, purifier regeneration cycles and electrochemical experiments through a potential setup through the glovebox.
Contact
Daasbjerg Group
Novo Nordisk Foundation CO2 Research Center (CORC)
Aarhus University
Contact information for Prof. Kim Daasbjerg
Email: kdaa@chem.au.dk
